Fig. 1: Nedd4-2 expression is reduced in db/db kidneys.
From: Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice
qPCR for Nedd4-2 in kidneys of n = 5 individual mice at 4, 8, 12 and 16 weeks (w) normalised to TBP housekeeping gene: males (A) or females (B). C Male whole kidney lysates (n = 3 each genotype) assessed for NEDD4-2 and quantitated relative to β-actin in (D). E Female whole kidney lysates (n = 3 each genotype) assessed for NEDD4-2 and quantitated relative to β-actin in (F). Data presented as mean ± SEM for qPCR and mean ± SD for immunoblots, analysed by one-way ANOVA. *P < 0.05, **P < 0.01, ***P < 0.005, ****P < 0.001.
