Table 1 Urine and serum analysis of mice.
From: Nedd4-2 ablation in kidney improves glycaemic control in diabetic mice
| Â | WT | N42K | db/db | N42K;db/db |
|---|---|---|---|---|
URINE | ||||
 Osmolarity (mOsmol/kg) | 1920.33 ± 150.40 (3) | 449.00 ± 181.44**** (4) | 1280.00 ± 256.14* (5) | 1166.00 ± 270.64** (5) |
 Creatinine (Cr) (mM) | 3.15 ± 1.05 (4) | 0.45 ± 0.26**** (4) | 0.26 ± 0.13**** (5) | 0.54 ± 0.31**** (5) |
 Na+/Cr (103) | 49.500 ± 19.50 (4) | 113.25 ± 80.63 (4) | 121.00 ± 24.99 (4) | 63.00 ± 21.66 (5) |
 K+/Cr (103) | 96.85 ± 9.12 (4) | 171.23 ± 16.78 (4) | 291.40 ± 87.99** (4) | 204.32 ± 23.36 (5) |
SERUM | ||||
 Urea (mmol/L) | 7.45 ± 1.07 (4) | 16.90 ± 5.17** (4) | 11.74 ± 2.64 (5) | 10.08 ± 2.27 (4) |
 Creatinine (mmol/L) | 11.00 ± 1.63 (4) | 19.75 ± 3.20* (4) | 5.75 ± 0.96 (4) | 14.00 ± 7.39 (4) |
 Na+ (mM) | 149.00 ± 4.08 (4) | 155.00 ± 1.15 (4) | 143.20 ± 6.91 (5) | 151.80 ± 5.76 (5) |
 K+ (mM) | 8.80 ± 3.98 (3) | 8.30 ± 0.72 (4) | 8.88 ± 0.43 (3) | 9.36 ± 0.71 (3) |
 Ca2+ (mM) | 2.58 ± 0.21 (4) | 3.03 ± 0.19 (4) | 2.59 ± 0.44 (5) | 2.52 ± 0.59 (4) |
 HCO3− (mM) | 21.00 ± 3.92 (4) | 26.67 ± 2.08 (3) | 18.60 ± 4.67 (5) | 18.50 ± 1.91 (4) |
 Glucose (mM) | 16.95 ± 2.24 (4) | 14.33 ± 2.59 (3) | 38.68 ± 3.53**** (5) | 21.30 ± 4.96 (4) |
 Globulin (g/L) | 37.00 ± 1.83 (4) | 41.67 ± 3.51 (3) | 41.00 ± 3.81 (5) | 44.25 ± 3.86* (4) |
 Albumin (g/L) | 15.25 ± 2.06 (4) | 17.00 ± 0.00 (3) | 17.60 ± 1.67 (5) | 17.75 ± 2.50 (4) |
 Protein (g/L) | 52.25 ± 2.63 (4) | 57.00 ± 4.40 (4) | 58.60 ± 5.32 (5) | 62.80 ± 5.63* (5) |
