Fig. 7: Additive effect of simvastatin plus chemotherapeutic drug treatment in SHH- and G3/G4-MB cells. | Cell Death & Disease

Fig. 7: Additive effect of simvastatin plus chemotherapeutic drug treatment in SHH- and G3/G4-MB cells.

From: Simvastatin suppresses spinal cord metastasis of medulloblastoma at clinically significant doses

Fig. 7

Viability of UW228-2 and ICb-1299 spheroids after 7- day and 14-day treatment with simvastatin (2 and 5 µM), with or without 0.5 nM vincristine (A), 1.98 nM cisplatin (B) or 1 μM etoposide (C). One-way ANOVA performed with Tukey’s post-hoc comparisons: (*) P < 0.05; (**) P < 0.001; (****) P < 0.0001.

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