Fig. 5: The interaction between PLIN2 and CD36.
From: PLIN2 promotes colorectal cancer progression through CD36-mediated epithelial-mesenchymal transition
A Western blot analysis showed that PLIN2 increased the expression level of CD36 protein in RKO and SW480 cells. B Quantification of the protein expression of CD36 represented in (C). C qRT‒PCR showed that PLIN2 increased the expression level of CD36 protein in RKO and SW480 cells. D Molecular docking simulation of PLIN2 (blue) and CD36 (pink) (left). Amino acid sites and reciprocal hydrogen bonds (yellow) and salt bridges (purple) of PLIN2 and CD36 interaction (right). E Immunofluorescence assays were performed to detect co-localization of PLIN2 with CD36. F Co-IP showed a direct interaction between CD36 and PLIN2 in RKO and SW480 cells. Data are shown as mean ± SD. **p < 0.01, ***p < 0.001.
