Fig. 4: Validation of the relationship between CXCL1 and the NF-κB signaling pathway. | Cell Death & Disease

Fig. 4: Validation of the relationship between CXCL1 and the NF-κB signaling pathway.

From: Unraveling the Role of METTL3 in Helicobacter pylori-induced gastritis via m6A-CXCL1/NF-κB modulation

Fig. 4

A RT-qPCR screening of three si-CXCL1 sequences. B Western blot analysis of p-IκBα, IκBα, p-p65, and p65 protein expression levels in HPI-treated GES-1 cells. The bar charts represent the ratios of p-IκBα/IκBα and p-p65/p65 protein levels. C Immunofluorescence staining of CXCL1 and NF-κB expression levels in HPI-treated GES-1 cells, scale bar: 25 μm. Values are presented as the mean ± standard deviation, and all cell experiments were repeated three times. *** indicates P < 0.001.

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