Fig. 3: High glucose promotes cell proliferation, migration, invasion, and expression of FIBCD1 in BC cells. | Cell Death & Disease

Fig. 3: High glucose promotes cell proliferation, migration, invasion, and expression of FIBCD1 in BC cells.

From: Diabetes is causally associated with increased breast cancer mortality by inducing FIBCD1 to activate MCM5-mediated cell cycle arrest via modulating H3K27ac

Fig. 3

A Proliferation rate of MCF7 cells is higher under hyperglycemic (25 mM glucose) culture conditions than that under euglycemic (5 mM glucose) culture conditions determined by CCK8 assay. B Proliferation capacity of MDA-MB-231 cells is higher under hyperglycemia conditions than that of euglycemic conditions. C Proliferation of MCF7 cells is determined by cell counting assay. D Proliferation of MDA-MB-231 cells is examined by cell counting assay. E Hyperglycemia promotes migration ability of MCF7 cells. F. Hyperglycemia enhances migration capacity of MDA-MB-231 cells. G Hyperglycemia augments invasion potential of MCF7 cells. H Hyperglycemia increases invasion capability of MDA-MB-231 cells. Data are shown as mean ± SD, Student’s t test. *P < 0.05; **P < 0.01; ***P < 0.001.

Back to article page