Fig. 4: Identification of the potential target genes of H3K14la regulating ferroptosis after hemin treatment in vitro. | Cell Death & Disease

Fig. 4: Identification of the potential target genes of H3K14la regulating ferroptosis after hemin treatment in vitro.

From: H3K14 lactylation exacerbates neuronal ferroptosis by inhibiting calcium efflux following intracerebral hemorrhagic stroke

Fig. 4

A The binding density of H3K14la was visualized by deepTools: the heatmap presents different H3K14la binding peaks in N2A cells between Veh and hemin groups. B ChIP-Seq detected the genomic distribution of the H3K14la in the Veh and hemin-treated N2A cells at 12 h. C KEGG analyses of annotated targets of H3K14la modification in hemin treated group based on ChIP-Seq data. D The RNA-Seq results from 24 h in neurons treated with Hemin. E KEGG analysis of annotated targets based on the RNA-Seq data. F Venn diagram of RNA-Seq and ChIP-Seq. G KEGG analysis of annotated targets of H3K14la modification in hemin treated group based on ChIP-Seq data with RNA-Seq data.

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