Fig. 9: SNTB1 knockdown restored the promotion of GC metastasis in vivo by ZC3H13 overexpression.

A Effects of ZC3H13 overexpression and SNTB1 knockdown on GC cells proliferation in vivo. Tumor diameter was measured every 3 days, and the tumor volume (B) and weight (C) were determined. D Representative images of the effects of ZC3H13 overexpression and SNTB1 knockdown on lung and liver metastasis of GC cells. E Quantitative results of the number of nodules in lung and liver metastases. F H&E staining of lung and liver metastases (magnification, 40×). G The schematic diagram of the mechanism by which ZC3H13 promotes GC progression in this study. *P < 0.05, **P < 0.01, and ***P < 0.001 represent varying degrees of significance between the indicated groups.