Table 1 Clinical characteristics of patients with active CD and normal participants.

From: Peroxiredoxin 1 promotes intestinal inflammation by activating the NLRP3 inflammasome in macrophages through lysosomal disruption in Crohn’s disease

Clinical Characteristics

Normal participants

CD

Number

43

43

Gender (Male/Female)

28/15

30/13

Age, ya

46.65 ± 13.28

31.5 ± 11.66

Disease duration, ya

-

2.99 ± 3.61

Origin of surgical specimens, n (%)

-

28 (65)

Ileum

-

16

Colon

-

12

Disease location, n (%)

  

L1 (ileal)

-

18 (42)

L2 (colonic)

-

12 (28)

L3 (ileocolonic)

-

13 (30)

L4 (isolated upper disease)

-

0

Disease behavior, n (%)

  

B1(non-stricturing, non-penetrating)

-

23 (53)

B2 (stricturing)

-

12 (28)

B3 (penetrating)

-

8 (19)

Perianal complications, n (%)

-

12 (28)

Smoking history, n (%)

  

Never

32 (74)

38 (88)

Former

3 (7)

0

Current

8 (19)

5 (12)

Medication, n (%)

  

Mesalazine

-

13 (30)

Corticosteroids

-

4 (9)

Immunosuppressants

-

6 (14)

Infliximab

-

5 (12)

  1. CD Crohn’s disease.
  2. aData are expressed as mean ± SD.