Fig. 3: BAP31 is required for resistance to ER stress-mediated apoptosis in PD. | Cell Death & Disease

Fig. 3: BAP31 is required for resistance to ER stress-mediated apoptosis in PD.

From: BAP31 represses endoplasmic reticulum stress-mediated apoptosis and alleviates neurodegeneration in Parkinson’s disease

Fig. 3

A ER stress and apoptotic proteins expressions in MPTP-induced PD mice (n = 3). B ER stress and apoptotic proteins expressions in MPP+-induced PC12 cells (n = 3). C Overexpression of BAP31 inhibits ER stress and apoptosis in PD mice (n = 3). D Overexpression of BAP31 suppresses ER stress and apoptosis in PC12 cells (n = 3). E Interference with BAP31 promotes ER stress and apoptosis in PC12 cells (n = 3). F The ER stress inhibitor 4-PBA inhibits ER stress and apoptosis (n = 3). G TUNEL staining (Scale bar = 50 μm). *P < 0.05, **P < 0.01, #P < 0.05, ##P < 0.01, &&P < 0.01.

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