Fig. 5: PINK1 inhibits ER stress-mediated apoptosis in PD through BAP31 phosphorylation at Ser142. | Cell Death & Disease

Fig. 5: PINK1 inhibits ER stress-mediated apoptosis in PD through BAP31 phosphorylation at Ser142.

From: BAP31 represses endoplasmic reticulum stress-mediated apoptosis and alleviates neurodegeneration in Parkinson’s disease

Fig. 5

A ER stress and apoptotic protein expressions by co-transfecting with PINK1 overexpression and BAP31 interference in MPP+-induced PC12 cells (n = 3). B ER stress and apoptotic protein expressions by co-transfecting with PINK1 and BAP31 (WT, Ser142A and Ser142E) in MPP+-induced PC12 cells (n = 3). *P < 0.05, **P < 0.01, #P < 0.05, ##P < 0.01, $P<0.05, $$P < 0.01, &P < 0.05, &&P < 0.01.

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