Fig. 1: Induction of EMT in HK-2 cells by TGF-β1. | Cell Death Discovery

Fig. 1: Induction of EMT in HK-2 cells by TGF-β1.

From: Quantitative peptidomics of endogenous peptides involved in TGF-β1-induced epithelial mesenchymal transition of renal epithelial cells

Fig. 1

a Controlled (untreated) cells had cobblestone like morphology, whereas those treated with 5 ng/mL TGF-β1 for 48 h showed fibroblast-like morphology. Original magnification power = ×400. b, c Epithelial marker (ZO-1) was significantly decreased, whereas mesenchymal marker (vimentin) was significantly increased. GAPDH served as the protein loading control. Each bar represents mean ± SD of the data derived from three independent experiments. *p < 0.05 vs. control

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