Fig. 3: Integration of DNA methylation with expression data. | Cell Death Discovery

Fig. 3: Integration of DNA methylation with expression data.

From: Novel biomarker ZCCHC13 revealed by integrating DNA methylation and mRNA expression data in non-obstructive azoospermia

Fig. 3

a Heatmap comparison of inversely correlated expression and methylation. b Starburst plot integrating differential DNA methylation and gene expression analysis. Indicated are genes that are hypermethylated and down-regulated genes (red); hypomethylated and up-regulated genes (green); hypermethylated and up-regulated genes (blue); or hypomethylated and down-regulated genes (orange). c The top 12 most significantly enriched biological process categories and zinc-finger CCHC-type containing 13 (the top10 most significantly enriched KEGG pathways within genes showing significant DNA methylation changes associated with significant inverse gene expression changes

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