Fig. 5: Using PPI to infer core elements involved in NOA. | Cell Death Discovery

Fig. 5: Using PPI to infer core elements involved in NOA.

From: Novel biomarker ZCCHC13 revealed by integrating DNA methylation and mRNA expression data in non-obstructive azoospermia

Fig. 5

a Protein–protein interaction network for genes differentially expressed and DNA methylated in NOA. The red circles represent the hub genes with inversely correlated DNA methylation and gene expression. b KEGG pathway analysis of the PPI network. The pvalues were calculated using hypergeometric tests and corrected using the Benjamini–Hochberg adjustment. The corrected pvalues are expressed and presented as negative logarithms (base 10)

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