Fig. 1: High glucose enhances cell death by the apoptotic stimulus, TNF-α/CHX, independent of osmotic pressure.
From: Hyperglycemia potentiates a shift from apoptosis to RIP1-dependent necroptosis
a Cell death of U937 cells induced by the extrinsic apoptotic stimulus, TNF-α/CHX, is enhanced by high glucose. Enhancement of cell death does not occur in response to high levels of b mannitol or c sucrose. Two-way ANOVA, ***p < 0.001
