Fig. 2: Effect of ONC injury on CB2-GFP RGCs.
From: Subtype-specific response of retinal ganglion cells to optic nerve crush
a Representative images showing NeuN (red) and GFP (green) immunolabeled retinal flat-mounts from transgenic CB2-GFP mice. Images of ONC (1 day, 3 days, 7 days, 10 days and 14 days post injury) and naïve control eyes are shown. Scale bar = 50 μm. b Percent cell survival of CB2-GFP RGCs. There was a steady decline in cell survival throughout the time course with significant cell loss at each time point when normalized to naïve. The values are represented as mean ± SD (n = 4–5). (* comparison to naïve, # comparison between time points). ****, # # # # p < 0.0001, # # p = 0.002, # # # p = 0.0005 by One Way-ANOVA and Tukey’s post hoc test
