Fig. 4: Cell cycle shift by CsA at non-toxic doses. | Cell Death Discovery

Fig. 4: Cell cycle shift by CsA at non-toxic doses.

From: Cell cycle shift from G0/G1 to S and G2/M phases is responsible for increased adhesion of calcium oxalate crystals on repairing renal tubular cells at injured site

Fig. 4

a The confluent cell monolayers were treated with 1, 2, or 4 µM CsA for 12 h. Original magnification = ×200 for all panels. b The cells were then subjected to cell death analysis comparing to repairing and controlled cells. c,d Cell cycle analysis was performed on CsA-treated cells compared to repairing and controlled cells. Each bar represents mean ± SEM of the data obtained from three independent experiments. *p < 0.05 vs. controlled cells; #p < 0.05 vs. 1 µM CsA-treated cells; †p < 0.05 vs. 2 µM CsA-treated cells

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