Fig. 4: TREM-1 inhibits autophagy in ox-LDL-treated ECs. | Cell Death Discovery

Fig. 4: TREM-1 inhibits autophagy in ox-LDL-treated ECs.

From: Sirt6-induced autophagy restricted TREM-1-mediated pyroptosis in ox-LDL-treated endothelial cells: relevance to prognostication of patients with acute myocardial infarction

Fig. 4

a TREM-1 KI directly inhibited autophagosome formation. Scale bar: 100 μm. b TREM-1 KD abrogated ox-LDL-mediated autophagosome formation inhibition. Scale bar: 100 μm. c TREM-1 KI directly inhibited autophagic biomarkers expression. d TREM-1 KD abrogated ox-LDL-mediated autophagic biomarkers expression inhibition. N = 3

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