Fig. 4: Ox-LDL triggered NLRP3 inflammasome activation in MCs. | Cell Death Discovery

Fig. 4: Ox-LDL triggered NLRP3 inflammasome activation in MCs.

From: Celastrol attenuates ox-LDL-induced mesangial cell proliferation via suppressing NLRP3 inflammasome activation

Fig. 4

a Protein expression of NLRP3 and pro-caspase 1 was measured by western blot. b, c Densitometric analysis of the western blots. d Caspase 1 activity was measured by a caspase 1/ICE colorimetric assay. e, f The levels of IL-18 and IL-1β in the MC culture medium were detected by ELISA. The data are shown as the mean ± SD of three replicates. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the “0” control group

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