Fig. 2: Reversal of diabetes-induced bone loss in miR-214-3p knockout mice. | Cell Death Discovery

Fig. 2: Reversal of diabetes-induced bone loss in miR-214-3p knockout mice.

From: High-glucose-induced miR-214-3p inhibits BMSCs osteogenic differentiation in type 1 diabetes mellitus

Fig. 2

a Representative micro-CT images of distal femur from WT and miR-214-3p knockout mice treated with or without STZ. Quantitative analysis of μCT parameters, including b bone volume per total volume; BV/TV, c trabecular thickness; Tb.Th, d trabecular number; Tb.N. Scale bars, 1 mm. e Representative images of new bone formation assessed by Red-calcein double labeling in WT and miR-214-3p knockout mice treated with or without STZ. Scale bars, 10 μm. All data are expressed as mean ± SEM, n = 6, **p < 0.01

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