Fig. 3: Total number of spontaneous “EEG seizure” events from wild-type and ALG13KO mice without any external intervention (EEGs were recorded for 2 weeks).
From: ALG13 participates in epileptogenesis via regulation of GABAA receptors in mouse models
a “EEG seizure” events were detected in C57BL/6J mice implanted with cortical electrodes. Numbers in the first column indicate animal identifiers. Subsequent columns indicate the day during the recording period. Each individual box is color coded according to the legend. Each of the numbers in these boxes indicates the total number of events per day. b Example of an event, defined as a high amplitude (>3 times baseline) rhythmic discharge, frequency (>5 Hz), and lasting longer than 5 s. Bar, 1 mV, 1 s. c Representative traces of EEG activity in WT and ALG13KO mice without any external intervention. Bar, 1 mV, 15 min. d Spectrograms of representative EEG recordings from wild-type and ALG13KO mice during baseline. e FFT of EEG recordings comparing ALG13KO and wild-type mice (***P < 0.001, two-way ANOVA test, n = 6)). f Comparison of average δ and θ power between wild-type and ALG13KO mice (***P < 0.001, two-sided unpaired T-test, n = 6).
