Fig. 5: IL-34 enhances the RNA transcripts of markers of type 2-polarized macrophages.
From: Macrophages produce and functionally respond to interleukin-34 in colon cancer
A Tumor-infiltrating cells (TICs) were either left unstimulated (Unst) or stimulated with increasing doses of human IL-34 (25–100 ng/ml) for 6 h. CD163, CD206, INOS, and IL-10 RNA transcripts were analyzed by real-time PCR, and levels were normalized to β-actin. Data are expressed as mean ± SEM of eight experiments. B LPMCs were isolated from non-tumoral samples of CRC patients and either left unstimulated (Unst) or stimulated with increasing doses of human IL-34 (25–100 ng/ml) for 6 h. CD163, CD206, INOS, and IL-10 RNA transcripts were analyzed by real-time PCR, and levels were normalized to β-actin. Data are expressed as mean ± SEM of five experiments.
