Fig. 2: Infusion of MSCs upregulates CD34+ hematopoietic stem cells in various organs. | Cell Death Discovery

Fig. 2: Infusion of MSCs upregulates CD34+ hematopoietic stem cells in various organs.

From: Mesenchymal stem cells protect against malaria pathogenesis by reprogramming erythropoiesis in the bone marrow

Fig. 2

Balb/c mice were infected with Plasmodium berghei and a group of mice received MSCs followed by Pb infection. These animals were sacrificed on day 7 post-infection and cells from various lymphoid organs were isolated and stained for CD3, CD19, Sca-1 and CD34 cell surface markers. The histogram represents the percentage of Sca-1+CD34+ cells in the spleen (A) and lymph node (B) (n = 9). Statistical significance was determined by unpaired two-tailed Student’s t-test; **p < 0.01 and ***p < 0.005.

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