Fig. 5: Enhanced T cell responses in the spleen of mice infected with malaria parasites are mediated by MSCs. | Cell Death Discovery

Fig. 5: Enhanced T cell responses in the spleen of mice infected with malaria parasites are mediated by MSCs.

From: Mesenchymal stem cells protect against malaria pathogenesis by reprogramming erythropoiesis in the bone marrow

Fig. 5

Balb/c mice were infected with malaria parasites and on day 7 post-infection spleen CD4+ T cells were purified and co-cultured with lineage-depleted cells from splenocytes of infected or uninfected mice at a 2:1 ratio and activated with anti-CD3 antibodies (A) or malarial antigens (B). Proliferation was measured after 72 h by 3[H]-thymidine incorporation for 16 h by using scintillation beta-counter. Data shown are mean value ± SD.

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