Fig. 2: Cellular phenotype of parent, NF2-KO, p16-KO, and NF2/p16-DKO-Met-5A and HOMC-B1 cells. | Cell Death Discovery

Fig. 2: Cellular phenotype of parent, NF2-KO, p16-KO, and NF2/p16-DKO-Met-5A and HOMC-B1 cells.

From: Identification of CD24 as a potential diagnostic and therapeutic target for malignant pleural mesothelioma

Fig. 2

a MTT analysis of the growth rate in parental cells, NF2-KO cell clones, p16-KO cell clones, and NF2/p16-DKO cell clones. Data are mean ± SEM (n = 3). *P < 0.05, statistically significant difference between parental and DKO cells. b Representative soft agar colony formation assays are shown. Right bar graphs represent the number of stained colonies. Scale bar = 100 μm. Data represent mean ± SEM (n = 3). *P < 0.05, statistically significant difference. c Representative migration assays using a Boyden chamber are shown. The right bar graph represents the number of stained colonies. Scale bar = 200 μm. Data represent mean ± SEM (n = 3). Asterisks (*) indicate statistically significant differences (*P < 0.05).

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