Fig. 4: Effects of the pBMSC-EXOs on the migration and proliferation of chondrocytes.

A The proliferation of chondrocytes in coculture with pBMSCs and BMSCs. B Western blot analysis of the exosome-specific CD9, CD63, and TSG101 proteins. C Morphology of the exosomes under transmission electron microscopy. Scale bars, 100 nm. D Wound-healing assays. E pBMSC-EXOs stimulated the migration of chondrocytes in the coculture system. Scale bars, 50 μm.