Fig. 2: KCNA1 and GPC1 were downregulated in the placenta of PE patients. | Cell Death Discovery

Fig. 2: KCNA1 and GPC1 were downregulated in the placenta of PE patients.

From: Elevated microRNA-125b inhibits cytotrophoblast invasion and impairs endothelial cell function in preeclampsia

Fig. 2

a, b mRNA expression of KCNA1 (a) and GPC1 (b) in placentas derived from PE patients (n = 15) and matched control (Ctrl, n = 29) were detected by real-time qPCR. c Western blot was carried out to measure protein expression of KCNA1 and GPC1 in the placenta of PE patients. Image J was used to quantify relative density. Statistical analysis of protein expression of KCNA1 (d) and GPC1 (e) in placentas derived from PE patients (n = 15) and matched control (Ctrl, n = 29) were presented using Graphpad Prism 7.0. The inverse correlation between miR-125b and KCNA1 (f), GPC1 (g) expression in the placenta of studied individuals is shown. All data are represented as mean ± SEM, *p < 0.05.

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