Fig. 3: KCNA1 and GPC1 were localized in human placenta villi. | Cell Death Discovery

Fig. 3: KCNA1 and GPC1 were localized in human placenta villi.

From: Elevated microRNA-125b inhibits cytotrophoblast invasion and impairs endothelial cell function in preeclampsia

Fig. 3

Immunohistochemistry was performed on paraffin sections of human placenta villi (a, b) at early gestation and preeclamptic placenta at term placenta (c–f). At early pregnancy, the positive immunoreactivity for KCNA1 was mainly located in various trophoblast cells, including cytotrophoblast cells and syncytiotrophoblast cells (a), while GPC1 was predominantly observed in vascular endothelial cells (b). At term placenta, KCNA1 remained in various trophoblast cells (c–e), while GPC1 mainly located in vascular endothelial cells (d–f). CTB cytotrophoblast cells, EVT extravillous trophoblast cells, EC vascular endothelial cells.

Back to article page