Fig. 3: Expression of XBP-1 is decreased in miR-674-5p-treated human IECs. | Cell Death Discovery

Fig. 3: Expression of XBP-1 is decreased in miR-674-5p-treated human IECs.

From: MicroRNA-674-5p induced by HIF-1α targets XBP-1 in intestinal epithelial cell injury during endotoxemia

Fig. 3

a Two-dimensional hierarchical clustering for apoptosis-, autophagy-, and endoplasmic reticulum (ER) stress-related genes among human IECs-FHC cells in 24 h after transfected with miR-674-5p or scrambled treatment. Fold changes in mRNA levels in FHC cells treated with miR-674-5p or scrambled are represented by green and red squares, showing decreased and increased levels, respectively. b Apoptosis-, autophagy-, and ER stress-related genes among human IECs-FHC cells in 24 hours after transfected with with miR-674-5p or scrambled treatment. The ratio represents the expression value in FHC cells with miR-674-5p-treated FHC cells compared with scramble-treated FHC cells.

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