Fig. 1: CdLS brain abnormalities in hindbrain-derived structures correlate with cognitive and behavioral alterations. | Cell Death Discovery

Fig. 1: CdLS brain abnormalities in hindbrain-derived structures correlate with cognitive and behavioral alterations.

From: Lithium as a possible therapeutic strategy for Cornelia de Lange syndrome

Fig. 1

A MRI data distribution in the cohort of CdLS patients. Purple: MRI negative (35/66); mauve: MRI positive—single anomalies (16/66); pink: MRI positive—multiple anomalies (15/66). B CNS anomalies and intellectual disabilities. Solid mauve: MRI negative; striped mauve: MRI anomalies. C CNS anomalies and behavioral disabilities—autistic traits. Solid purple: MRI negative; striped purple: MRI anomalies; solid mauve: MRI negative; striped mauve: Rhombencephalon derivation; dotted mauve: Prosencephalon derivation. *p < 0.05; * vs MRI negative.

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