Fig. 5: Human 90K (LGALS3BP) expression is associated with poor prognosis and directly correlates with TGF-β1 and USFs. | Cell Death Discovery

Fig. 5: Human 90K (LGALS3BP) expression is associated with poor prognosis and directly correlates with TGF-β1 and USFs.

From: Tgf-β1 transcriptionally promotes 90K expression: possible implications for cancer progression

Fig. 5

Using the public cancer database cBioPortal, the TCGA PanCancer Atlas cohort of patients affected by clear cell renal cell carcinoma (ccRCC) was analyzed (N = 512). In A, Kaplan–Meier curves of disease-specific OS stratified by high (EXP > 1) or low (EXP < 1) expression of LGALS3BP. In B, patients were stratified by TGF-β1 expression; in C, by USF1 expression; and in D, by concomitant LGALS3BP/TGF-β1 high or low expression. In E, scatterplot correlation between LGALS3BP and TGF-β1 (left), LGALS3BP and USF1 (middle); LGALS3BP and USF2 (right), as visualized by cBioPortal. In F, table elaborated by cBioPortal showing tendency of co-occurrence among 90K, TGF-β1, and USF1.

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