Fig. 4: SPOP is negatively correlated with SUFU in ccRCC. | Cell Death Discovery

Fig. 4: SPOP is negatively correlated with SUFU in ccRCC.

From: SPOP–PTEN–SUFU axis promotes progression of clear cell renal cell carcinoma via activating SHH and WNT pathway

Fig. 4

A, B The statistical results for IHC staining of SPOP and SUFU among 16 different cancer types in human tissue microarrays. C, D Representative IHC staining for SPOP and SUFU in ccRCC tissues and normal adjacent tissues. E Spearman correlation analysis indicated that the mRNA level of SUFU was also negatively correlated with SPOP in ccRCC in GEO database (GSE73731). F Kaplan–Meier survival analysis of overall survival rate of ccRCC patients with high or low SUFU mRNA expression performed by using a dataset from Kaplan–Meier plotter.

Back to article page