Fig. 3: The effect of the overexpression or knockdown of miR-5000-3p and treatment with or without OXA on cell invasion, migration, and apoptosis of HCT116 and LoVo or OR-HCT116 and OR-LoVo cells in vitro. | Cell Death Discovery

Fig. 3: The effect of the overexpression or knockdown of miR-5000-3p and treatment with or without OXA on cell invasion, migration, and apoptosis of HCT116 and LoVo or OR-HCT116 and OR-LoVo cells in vitro.

From: miR-5000-3p confers oxaliplatin resistance by targeting ubiquitin-specific peptidase 49 in colorectal cancer

Fig. 3

A Representative images and bar graphs showing the effects of miR-5000-3p overexpression or knockdown on cell invasion of HCT116 and LoVo or OR-HCT116 and OR-LoVo cells. B Effects of miR-5000-3p overexpression or knockdown on cell invasion of HCT116 and LoVo or OR-HCT116 and OR-LoVo cells were measured by wound-healing assays. C Effects of miR-5000-3p overexpression or knockdown on cell apoptosis of HCT116 and LoVo or OR-HCT116 and OR-LoVo cells were measured by flow cytometer assays. *p < 0.05, **p < 0.01, and ***p < 0.001; #p < 0.05, ##p < 0.01, and ###p < 0.001.

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