Fig. 4: miR-5000-3p regulates cell proliferation and tumor growth. | Cell Death Discovery

Fig. 4: miR-5000-3p regulates cell proliferation and tumor growth.

From: miR-5000-3p confers oxaliplatin resistance by targeting ubiquitin-specific peptidase 49 in colorectal cancer

Fig. 4

A–C HCT116 and OR-HCT116 cells were subcutaneously injected into nude mice. Tumor volumes (B) were measured at indicated days. Mice were sacrificed after 5 weeks. Tumor images were acquired as shown in (A) and tumor weights were measured as shown in (C). n = 5. D The mRNAs were extracted from the cells for miR-5000-3p detection and subjected to qRT-PCR. E Representative images and histogram of data statistics of immunohistochemical (IHC) staining of KI-67 in tumor tissues among different groups. Scale bar = 50 µm. *p < 0.05, **p < 0.01, and ***p < 0.001.

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