Fig. 5: Anti-PD-1 immunotherapy enhances the response to CDDP in OC. | Cell Death Discovery

Fig. 5: Anti-PD-1 immunotherapy enhances the response to CDDP in OC.

From: Cisplatin remodels the tumor immune microenvironment via the transcription factor EB in ovarian cancer

Fig. 5

A Schematic representation of the treatment is shown. B Comparison of tumor growth in different groups. C The mice were necropsied at day 24, and tumors are shown. D Comparison of tumor weights in different groups. E TILs were isolated and stained with CD8 and Granzyme B. Percentages of CD8+ Granzyme B + were shown. F TILs were isolated and stained with CD8 and Granzyme B. Representative scatter diagram were shown. G H&E and immunohistochemical staining of Ki67, TFEB, PD-L1, and HLA-A within tumor tissues. Scale bars = 100 μm. Data are expressed as mean ± standard deviation. *p < 0.05; **p < 0.01; ***p < 0.001.

Back to article page