Fig. 2: NR4A1 reduces apoptosis and JNK phosphorylation incurred by TG or H2O2 in MIN6 cells. | Cell Death Discovery

Fig. 2: NR4A1 reduces apoptosis and JNK phosphorylation incurred by TG or H2O2 in MIN6 cells.

From: NR4A1 enhances MKP7 expression to diminish JNK activation induced by ROS or ER-stress in pancreatic β cells for surviving

Fig. 2

A–B The relative NR4A1 protein levels in both OV (NR4A1 overexpression) and NC (control) cells were assayed with Western Blotting. C–D The relative cell viability in response to 100 μM H2O2 or 0.5 μM TG at various time points in both OV and NC cells was assayed with CCK8. E–F The protein levels of relative cleaved caspase-3 in response to 100 μM H2O2 or 0.5 μM TG at various time points in both OV and NC cells were obtained with western blotting. G–H The protein levels of p-JNK in response to 100 μM H2O2 or 0.5 μM TG at various time points in both OV and NC cells were shown in western Blotting. These data represented the means of three independent experiments, *P < 0.05, **P < 0.01 vs. ns. Error bars were shown as SD values.

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