Table 1 Expression and prognosis values of WWP1 in human cancers.
From: The emerging role of WWP1 in cancer development and progression
Cancer type | Expression level of tumor | Clinicopathological features and prognosis values | Reference |
|---|---|---|---|
Colorectal cancer | Increased | High expression of WWP1 was related with tumor size, T classification, TNM stage, distant metastasis and poor survival | [23] |
Osteosarcomas | Upregulated | WWP1 expression was associated with single-nucleotide polymorphisms and copy number variants | |
Oral cancer | Upregulated | N/A | [25] |
Gastric cancer | Increased | High expression of WWP1 was associated with TNM stage, lymph node metastasis, invasive depth and poor prognosis | [26] |
Melanoma | Poor expression | N/A | [27] |
Prostate cancer | Upregulated | N/A | |
Breast cancer | Upregulated | Patients with only nuclear-localized WWP1 in tumors had favorable prognosis. And low/absent WWP1 level indicated the worst prognosis | |
Hepatocellular cancer | Elevated | WWP1 level was linked to tumor size, histological grade, TNM stage, vascular invasion and tumor capsule, poorer prognosis | |
Chronic lymphocytic leukemia | Higher | High expression of WWP1 was related with adverse prognostic factors including CD38 and ZAP-70 | [38] |
Cutaneous squamous cell carcinoma | Augmented | High expression of WWP1 was associated with histological grade, invasion depth, lymph node metastasis and unfavorable prognosis | [39] |
