Fig. 6: Suppression of GSTA2 expression inhibited the growth and metastasis of HCC. | Cell Death Discovery

Fig. 6: Suppression of GSTA2 expression inhibited the growth and metastasis of HCC.

From: Glutathione S-transferase A2 promotes hepatocellular carcinoma recurrence after liver transplantation through modulating reactive oxygen species metabolism

Fig. 6

A Stable GSTA2-suppressing MHCC97L HCC cell (97L in short) exhibited significant down-regulation of GSTA2 mRNA and protein. B MTT proliferation assay for control and GSTA2-suppressing HCC cells. C Matrigel invasion assay for control and GSTA2-suppressing HCC cells. Scale bar: 200 μM. D Xenograft subcutaneous tumor model in nude mice. E H&E staining of lung tissues in metastatic tumor. The dashed circle indicates the presence of an HCC tumor in the lung. Scale bar: 100 μM. Control, MHCC97L-shControl stable cells; shGSTA2, MHCC97L-shGSTA2 stable cells; NS, no significance; *P < 0.05; **P < 0.01.

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