Table 1 Research application of RBM39 in tumor.
From: RNA-binding protein 39: a promising therapeutic target for cancer
Cancer | Expression | Related Function | Refs |
|---|---|---|---|
Ewing Sarcoma | Up | Regulates proliferation and protein synthesis pathways | [1] |
Breast cancer | Up | Mediates VEGF alternative splicing | [2] |
TNBC | Up | Regulates DNA repair, cell apoptosis and cell cycle | |
Invasive ductal carcinoma | Up | Transfers from the cytoplasm to the nucleus | [5] |
Colorectal adenoma | Up | Mediates cell viability | [6] |
Up | Affects cell survival and viability | [7] | |
Hepatocellular carcinoma | Up | Related to the appearance of microvessels | [8] |
Prostate cancer | Down | Cancer cell migration and invasion | [9] |
Myeloma malignancy | Up | Regulates mTOR signaling, promotes cell proliferation | [10] |
AML | Up | Causes changes in the splicing of HOXA9 target genes | [11] |
Lung cancer | Up | Promotes proliferation and migration | [12] |
