Fig. 3: Potentially druggable protein targets from LM and LuM CD11b+ cells with correlating transcriptomic data. | Cell Death Discovery

Fig. 3: Potentially druggable protein targets from LM and LuM CD11b+ cells with correlating transcriptomic data.

From: Proteomic signatures of myeloid derived suppressor cells from liver and lung metastases reveal functional divergence and potential therapeutic targets

Fig. 3

The drug–gene interaction database (DGIdb) and PHAROs drug–target development data mining platforms highlight possible targets for future validation experiments and translational studies based on current protein knowledge (A and B). Positive correlating proteomic and transcriptomic data (C) show possible targets for future MDSC modulating strategies for LuM- or LM-specific MDSCs. Data shown n = 4 per tissue type mean +/− SEM.

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