Table 2 Univariate and multivariate analysis of overall survival.
From: B7-H5 blockade enhances CD8+ T-cell-mediated antitumor immunity in colorectal cancer
Characteristic | Univariate | P value | Characteristic | Multivariate | P value |
|---|---|---|---|---|---|
HR (95% CI) | HR (95% CI) | ||||
Gender | Gender | ||||
Male vs female | 1.022 (0.592–1.764) | 0.937 | Male vs female | 0.96 (0.503–1.835) | 0.903 |
Age | Age | ||||
<70 vs ≥70 | 2.122 (1.175–3.833) | 0.013 | <70 vs ≥70 | 1.932 (1.008–3.704) | 0.047 |
T stage | T stage | ||||
T1/T2 vs T3/T4 | 2.42 (0.588–9.958) | 0.221 | T1/T2 vs T3/T4 | 2.047 (0.476–8.805) | 0.336 |
N stage | N stage | ||||
N0 vs N1/N2 | 2.847 (1.638–4.949) | 0.0002 | N0 vs N1/N2 | 2.391 (1.272–4.493) | 0.007 |
B7-H5 expression | B7-H5 expression | ||||
Low vs high | 2.479 (1.369–4.488) | 0.003 | Low vs high | 1.984 (1.058–3.718) | 0.033 |
CD8 infiltration | CD8 infiltration | ||||
Low vs high | 0.387 (0.215–0.696) | 0.002 | Low vs high | 0.478 (0.258–0.888) | 0.019 |
Pathological grading | Pathological grading | ||||
Moderate vs poor | 1.506 (0.874–2.597) | 0.14 | Moderate vs poor | 1.54 (0.854–2.775) | 0.151 |
