Fig. 7: Downregulation of NEAT1 and overexpression of miR-139-5p alleviates hepatic fibrosis in mice. | Cell Death Discovery

Fig. 7: Downregulation of NEAT1 and overexpression of miR-139-5p alleviates hepatic fibrosis in mice.

From: miR-139-5p sponged by LncRNA NEAT1 regulates liver fibrosis via targeting β-catenin/SOX9/TGF-β1 pathway

Fig. 7

A The expression levels of NEAT1 was examined in liver tissues from fibrotic mice transfected with Ad-Con or Ad-shNEAT1. n = 6/group. B The expression levels of miR-139-5p in liver tissues from fibrotic mice transfected with agomir control and ago-miR-139-5p were examined by qRT-PCR. n = 6/group. C The expression levels of miR-139-5p in liver tissues from fibrotic mice transfected with Ad-Con or Ad-shNEAT1 were detected. n = 6/group. D The liver tissues from fibrotic mice transfected with Ad-Con or Ad-shNEAT1 were treated with Masson staining and Sirius red staining, n = 6/group, original magnification×200. E The liver tissues from fibrotic mice infected with agomir control and ago-miR-139-5p were treated with Masson staining and Sirius red staining, n = 6/group, original magnification×200. Graph represents mean ± SD. *P < 0.05, **P < 0.01.

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