Table 2 Antioxidants alleviate the progression of RILI.
From: Radiation-induced liver injury and hepatocyte senescence
Antioxidants | Natural or synthetic | Mechanism | RILI models | Type of radiation | Dose | Ref |
|---|---|---|---|---|---|---|
Salen Mn complex (EUK-189 and EUK-207) and Mn porphyrins | Synthetic | Novel Synthetic SOD/Catalase Mimetics possess superoxide dismutase (SOD), catalase and peroxidase activities. | Capillary endothelial cells | X-ray | 2-50 Gy | [28] |
GC4401 | Synthetic | Highly specific superoxide dismutase mimic | Mice | γ-ray | 4 Gy | [29] |
P. ginseng water extract | Natural | / | Mice | X-ray | 15 Gy | [30] |
Epicatechin | Natural | / | Mice | γ-ray | 5 Gy | [31] |
Betaine | Natural | / | Rats | γ-ray | 9 Gy | [32] |
Date syrup | Natural | / | Rats | γ-ray | 6 Gy | [102] |
Persimmon leaf | Natural | / | Rats | γ-ray | 6 Gy | [100] |
Grape seed oil | Natural | / | Rats | γ-ray | 7 Gy | [101] |
Flaxseed oil | Natural | / | Mice | γ-ray | 5 Gy | [96] |
Astragalus polysaccharide | Natural | / | Mice | γ-ray | 5 Gy | [55] |
