Fig. 6: No remarked changes of other pathways (JNK, ERK, P38) in sciatic nerves after MPTP and CU-CPT22 challenging. | Cell Death Discovery

Fig. 6: No remarked changes of other pathways (JNK, ERK, P38) in sciatic nerves after MPTP and CU-CPT22 challenging.

From: Phosphorylated α-synuclein aggregated in Schwann cells exacerbates peripheral neuroinflammation and nerve dysfunction in Parkinson’s disease through TLR2/NF-κB pathway

Fig. 6

A Western blotting analysis of p-JNK and JNK. B Western blotting analysis of p-ERK and ERK. C Western blotting analysis of p-P38 and P38. The β-actin was used as housekeeping and data were normalized to β-actin expression. Data were presented as mean ± SEM and analyzed by one-way ANOVA followed by Tukey’s post hoc test; n = 6. MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; JNK: c-Jun N-terminal kinase; p-JNK: phospho-JNK; ERK: extracellular regulated protein kinases; p-ERK: phospho-ERK; p-P38: phospho-P38; SEM: standard error of the mean; ANOVA: analysis of variance.

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