Fig. 6: TM7SF2 modulates cell proliferation and apoptosis via C-Raf/ERK signaling pathway in cervical cancer cells. | Cell Death Discovery

Fig. 6: TM7SF2 modulates cell proliferation and apoptosis via C-Raf/ERK signaling pathway in cervical cancer cells.

From: TM7SF2 regulates cell proliferation and apoptosis by activation of C-Raf/ERK pathway in cervical cancer

Fig. 6

A The inhibitory effect of C-Raf/ERK pathway after treatment with Raf inhibitor LY3009120 in C33A cells. B, C CCK-8 assay and colony formation assay showed that LY3009120 reversed TM7SF2-induced promotion of proliferation in C33A cells. D The flow cytometry assay showed that LY3009120 treatment rescued the suppression of apoptosis by TM7SF2 overexpression in C33A cells. *p < 0.05 compared to control cDNA, #p < 0.05 compared to control cDNA+ LY3009120, Δp < 0.05 compared to TM7SF2 cDNA.

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