Fig. 5: Knockdown TMEM161B-AS1 inhibited the proliferation, migration, invasion of glioma cells and promoted apoptosis. | Cell Death Discovery

Fig. 5: Knockdown TMEM161B-AS1 inhibited the proliferation, migration, invasion of glioma cells and promoted apoptosis.

From: Over-expression of lncRNA TMEM161B-AS1 promotes the malignant biological behavior of glioma cells and the resistance to temozolomide via up-regulating the expression of multiple ferroptosis-related genes by sponging hsa-miR-27a-3p

Fig. 5

a The TMEM161B-AS1 levels in U87, U251 and human astrocytes (HA) cells were detected by qRT-PCR. b The TMEM161B-AS1 levels in the Control, si-NC, si-TMEM161B-AS1 transfected U87 and U251 cells. c, d The cell viability of U87, U251 cells transfected with Control, si-NC and si-TMEM161B-AS1 were analyzed by Cell Counting Kit-8 assay. e, f The cell migration and invasion ability of Control, si-NC, si-TMEM161B-AS1 transfected U87 and U251 cells were detected by Transwell assay. g The apoptosis rate of Control, si-NC, si-TMEM161B-AS1 transfected U87 and U251 cells were detected by Flow cytometry. n = 3 per group.

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