Fig. 1: CircETFA is overexpressed in HCC tissues and cells. | Cell Death Discovery

Fig. 1: CircETFA is overexpressed in HCC tissues and cells.

From: CircETFA upregulates CCL5 by sponging miR-612 and recruiting EIF4A3 to promote hepatocellular carcinoma

Fig. 1

A circRNA microarray analysis with three pairs of total RNA from the plasma of HCC patients and healthy controls identified a total of 5122 differentially expressed circRNAs. B The heat map shows the normalized and log2-transformed signal values of the 40 circRNAs with the most obvious differential expression. C, D qRT-PCR detected expression of the most significant up-regulated ten circRNAs in HCC cell lines and tissues. E Sanger sequencing showed the splicing region of circETFA head and tail and determined its position and sequence in the genome. F RT-PCR excluded genome rearrangement. The data are shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.

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