Fig. 3: CircETFA alters proliferation, apoptosis, and the cell cycle in HCC cells.

A A schematic diagram of the overexpression vector construction of circETFA. B A schematic diagram of design of circETFA small interfering RNA and test result of knockdown efficiency. C–E Clone formation experiments and EdU assays were used to detect the influence of circETFA on HCC cell proliferation. F The effect of circETFA on apoptosis was analyzed by flow cytometry. G The effect of circETFA on the cell cycle was analyzed by flow cytometry. The data are shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.