Fig. 5: CircETFA upregulates CCL5 to affect PI3K/Akt signaling pathway. | Cell Death Discovery

Fig. 5: CircETFA upregulates CCL5 to affect PI3K/Akt signaling pathway.

From: CircETFA upregulates CCL5 by sponging miR-612 and recruiting EIF4A3 to promote hepatocellular carcinoma

Fig. 5

A GO analysis of the RNA-seq results. B Statistical results of the functional COG. C Heat maps were generated to show the FPKM values of the 50 most changed mRNAs converted by log10. D Relationship between circETFA expression and mRNAs levels in HCC tissues. E Detect changes in CCL5 expression by qRT-PCR after overexpression or knockdown of circETFA. F The protein levels of CCL5, Akt, p-Akt, FoxO6, CyclinD1, and MMP7 were measured by western blotting. The data are shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.

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