Fig. 4: RNA-sequencing of renal NLRP3 signaling following AKI. | Cell Death Discovery

Fig. 4: RNA-sequencing of renal NLRP3 signaling following AKI.

From: NLRP3 associated with chronic kidney disease progression after ischemia/reperfusion-induced acute kidney injury

Fig. 4

a Heatmap of 1417 DEGs screened by limma package. Red areas represent highly expressed genes and blue areas represent lowly expressed genes in 2 or 4 weeks post-IRI group, compared with sham controls. b Volcano plot analysis identifies DEGs. Red dots represent upregulated genes and green dots represent downregulated genes in 2 or 4 weeks post-IRI group, compared with sham controls. c The expression of NLRP3 signaling-associated genes NLRP3 signaling-associated genes in sham control or IRI groups. DEG differentially expressed gene, IRI Ischemia/reperfusion injury.

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